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rs3025786

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.6 slightly decreased Alzheimer's disease risk among ApoE4 carriers
(C;T) 1.6 slightly decreased Alzheimer's disease risk among ApoE4 carriers
(T;T) normal
ReferenceGRCh38 38.1/141
Chromosome14
Position73198010
GenePSEN1
is asnp
is mentioned by
dbSNPrs3025786
ebirs3025786
HLIrs3025786
Exacrs3025786
Varsomers3025786
Maprs3025786
PheGenIrs3025786
hapmaprs3025786
1000 genomesrs3025786
hgdprs3025786
ensemblrs3025786
gopubmedrs3025786
geneviewrs3025786
scholarrs3025786
googlers3025786
pharmgkbrs3025786
gwascentralrs3025786
openSNPrs3025786
23andMers3025786
23andMe allrs3025786
SNP Nexus

SNPshotrs3025786
SNPdbers3025786
MSV3drs3025786
GWAS Ctlgrs3025786
GMAF0.02893
Max Magnitude1.6
rs3025786 is a SNP in the presenilin 1 PSEN1 gene.

A study of a Spanish case-control sample of 1,183 individuals showed rs3025786 was associated with Alzheimer's disease in an ApoE-specific manner: more specifically rs3025786(C) allele carriers have a decreased AD risk among carriers of the ApoE4 allele. [PMID 18957849]