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rs31489(A;C)

From SNPedia

1.75-fold reduced risk of developing lung cancer
Is agenotype
ofrs31489
GeneCLPTM1L
Chromosome5
Position1,342,599
mentionedby
Magnitude2
ReputeGood
Geno Mag Summary
(A;A) 1.1 Reduced lung cancer risk?
(A;C) 2 1.75-fold reduced risk of developing lung cancer
(C;C) 2 Increased risk for lung cancer and emphysema


[PMID 20142248OA-icon.png] Cumulative effect of multiple Loci on genetic susceptibility to familial lung cancer

The frequency of the minor allele A of rs31489 was 32.49% in cancer patients versus 45.79% in disease-free subjects. Subjects carrying one copy of minor allele A are at 1.75-fold reduced risk of developing lung cancer.