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rs3217992

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1.24x increased myocardial infarction risk
(A;G) 1.24x increased myocardial infarction risk
(G;G) normal
ReferenceGRCh38 38.1/141
Chromosome9
Position22003224
GeneCDKN2B, CDKN2B-AS1
is asnp
is mentioned by
dbSNPrs3217992
ebirs3217992
HLIrs3217992
Exacrs3217992
Varsomers3217992
Maprs3217992
PheGenIrs3217992
hapmaprs3217992
1000 genomesrs3217992
hgdprs3217992
ensemblrs3217992
gopubmedrs3217992
geneviewrs3217992
scholarrs3217992
googlers3217992
pharmgkbrs3217992
gwascentralrs3217992
openSNPrs3217992
23andMers3217992
23andMe allrs3217992
SNP Nexus

SNPshotrs3217992
SNPdbers3217992
MSV3drs3217992
GWAS Ctlgrs3217992
GMAF0.3595
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 25814643OA-icon.png] Genetic Variations in MicroRNA-Binding Sites Affect MicroRNA-Mediated Regulation of Several Genes Associated With Cardio-metabolic Phenotypes

rs3217992 is a SNP in the cyclin-dependent kinase inhibitor 2B CDKN2B gene. A study of 432 Han Chinese patients with myocardial infarctions concluded that male subjects carrying a rs3217992(A) allele were at 1.24x increased risk (for MI).[PMID 19272367]


[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease.

[PMID 23111177OA-icon.png] CDKN2B-AS1 Genotype-Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients From the United States

[PMID 20386740OA-icon.png] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

[PMID 20978019] CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection

[PMID 19559344] Genetic variants on chromosome 9p21 and ischemic stroke in Chinese

[PMID 19258477OA-icon.png] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

[PMID 18174243OA-icon.png] Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

[PMID 17459456OA-icon.png] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.


[PMID 27486979] Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.