Have questions? Visit https://www.reddit.com/r/SNPedia

rs339097

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs339097(C;C)
Make rs339097(C;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position128759170
GeneCALU
is asnp
is mentioned by
dbSNPrs339097
ebirs339097
HLIrs339097
Exacrs339097
Varsomers339097
Maprs339097
PheGenIrs339097
hapmaprs339097
1000 genomesrs339097
hgdprs339097
ensemblrs339097
gopubmedrs339097
geneviewrs339097
scholarrs339097
googlers339097
pharmgkbrs339097
gwascentralrs339097
openSNPrs339097
23andMers339097
23andMe allrs339097
SNP Nexus

SNPshotrs339097
SNPdbers339097
MSV3drs339097
GWAS Ctlgrs339097
GMAF0.04545
Max Magnitude0
? (C;C) (C;T) (T;T) 28
PharmGKB indicates that this SNP is relevant to Warfarin dosing. rs339097(G) is associated with 14.5% higher therapeutic warfarin dose in African Americans. This variant is also more common in African Americans with minor allele frequencies of 11–14% , but only 0.2% in Caucasians.


[PMID 21228733OA-icon.png] Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients.


GET Evidence
rs339097
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0859375
summary



[PMID 22676711OA-icon.png] Pharmacogenomics of warfarin in populations of African descent.


ClinVar
Risk rs339097(C;C)
Alt rs339097(C;C)
Reference rs339097(T;T)
Significance Drug-response
Disease warfarin response - Dosage
Variation info
Gene CALU
CLNDBN warfarin response - Dosage
Reversed 1
HGVS NC_000007.13:g.128399224A>G
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211348.1,