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rs33981382

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs33981382(A;G)
Make rs33981382(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position17342393
GenePADI4
is asnp
is mentioned by
dbSNPrs33981382
ebirs33981382
HLIrs33981382
Exacrs33981382
Varsomers33981382
Maprs33981382
PheGenIrs33981382
hapmaprs33981382
1000 genomesrs33981382
hgdprs33981382
ensemblrs33981382
gopubmedrs33981382
geneviewrs33981382
scholarrs33981382
googlers33981382
pharmgkbrs33981382
gwascentralrs33981382
openSNPrs33981382
23andMers33981382
23andMe allrs33981382
SNP Nexus

SNPshotrs33981382
SNPdbers33981382
MSV3drs33981382
GWAS Ctlgrs33981382
GMAF0.006887
Max Magnitude0
Venter snp
Source plos
Gene PADI4
allele G
frequency
sift AFFECT FUNCTION
HuRef 1103675034022
Disease Association PADI4 is thought to be a rheumatoid arthritis susceptibility locus (MIM:180300). Could have an important role in the pathogenesis of rheumatoid arthritis by increasing citrullination of proteins in rheumatoid arthritis synovial tissues, leading, in a cytokine-rich milieu, to a break in tolerance to citrullinated peptides processed and presented in the appropriate HLA context.