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rs351855(T;T)

From SNPedia

2x increased prostate cancer risk; among breast cancer patients, herceptin is less effective
Is agenotype
ofrs351855
GeneFGFR4
Chromosome5
Position177,093,242
mentionedby
Magnitude3.2
ReputeBad
Geno Mag Summary
(C;C) 0 normal
(C;T) 2 1.2x increased risk for prostate cancer
(T;T) 3.2 2x increased prostate cancer risk; among breast cancer patients, herceptin is less effective

Well replicated and confirmed by clinvar, this rare genotype of the fibroblast growth factor receptor 4 gene influences several forms of cancer progression and tumor cell motility. It is found in ~3% of people.