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rs35203445

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs35203445(G;G)
Make rs35203445(G;T)
ReferenceGRCh38 38.1/141
Chromosome16
Position176937
GeneHBA1
is asnp
is mentioned by
dbSNPrs35203445
ebirs35203445
HLIrs35203445
Exacrs35203445
Varsomers35203445
Maprs35203445
PheGenIrs35203445
hapmaprs35203445
1000 genomesrs35203445
hgdprs35203445
ensemblrs35203445
gopubmedrs35203445
geneviewrs35203445
scholarrs35203445
googlers35203445
pharmgkbrs35203445
gwascentralrs35203445
openSNPrs35203445
23andMers35203445
23andMe allrs35203445
SNP Nexus

SNPshotrs35203445
SNPdbers35203445
MSV3drs35203445
GWAS Ctlgrs35203445
Max Magnitude0
OMIM141800
Desc
Variant0112
Relatedalso
ClinVar
Risk rs35203445(G;G)
Alt rs35203445(G;G)
Reference rs35203445(T;T)
Significance Other
Disease HEMOGLOBIN OGI HEMOGLOBIN QUEENS
Variation info
Gene HBA1
CLNDBN HEMOGLOBIN OGI HEMOGLOBIN QUEENS
Reversed 0
HGVS NC_000016.9:g.226936T>G
CLNSRC OMIM Allelic Variant
CLNACC RCV000017133.2, RCV000017134.2,


[PMID 1299245OA-icon.png] A family case of beta-thalassemia minor and hemoglobin Queens: alpha 34 (B15) Leu-Arg.


[PMID 3446653] Decreased heat stability found in purified hemoglobin Queens [alpha 34(B15)Leu----Arg].


[PMID 7055587] A new electrophoretic variant of hemoglobin (Ogi) in which a leucine residue is replaced by an arginine residue at position 34 of the alpha-chain.


[PMID 7096112] Hemoglobin Queens (alpha 34 (B15) Leu replaced by Arg) found in two Chinese families.


[PMID 7158628] Hemoglobin Queens: alpha 34 (B15) Leu-Arg structural and functional properties and its association with Hb E.