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rs35767

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T)
Make rs35767(C;C)
Make rs35767(C;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position102481791
GeneIGF1
is asnp
is mentioned by
dbSNPrs35767
ebirs35767
HLIrs35767
Exacrs35767
Varsomers35767
Maprs35767
PheGenIrs35767
hapmaprs35767
1000 genomesrs35767
hgdprs35767
ensemblrs35767
gopubmedrs35767
geneviewrs35767
scholarrs35767
googlers35767
pharmgkbrs35767
gwascentralrs35767
openSNPrs35767
23andMers35767
23andMe allrs35767
SNP Nexus

SNPshotrs35767
SNPdbers35767
MSV3drs35767
GWAS Ctlgrs35767
GMAF0.2819
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 18761080] Absence of association between SNPs in the promoter region of the insulin-like growth factor 1 (IGF-1) gene and longevity in the Han Chinese population


[PMID 19784788] Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk

GWAS snp
PMID [PMID 20081858OA-icon.png]
Trait Fasting glucose-related traits
Title New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Risk Allele G
P-val 2E-9
Odds Ratio None None


[PMID 20490824OA-icon.png] A polymorphism near IGF1 is associated with body composition and muscle function in women from the Health, Aging, and Body Composition Study



[PMID 22253814OA-icon.png] A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme


[PMID 17300730OA-icon.png] Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.


[PMID 18199734OA-icon.png] IGF-I and IGF-II genetic variation and breast cancer risk in Chinese women: results from the Shanghai Breast Cancer Study.


[PMID 18250100] Identification of genetic variants that influence circulating IGF1 levels: a targeted search strategy.


[PMID 18596909OA-icon.png] IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).


[PMID 19124510OA-icon.png] Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.


[PMID 19147602] The -G1245A IGF1 polymorphism is related with small head size and less brain sparing in small for gestational age born children.


[PMID 19240240OA-icon.png] IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.


[PMID 19551864OA-icon.png] Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease.


[PMID 20039319OA-icon.png] IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort.


[PMID 20199671OA-icon.png] A microsatellite polymorphism in IGF1 gene promoter and longevity in a Han Chinese population.


[PMID 21046444OA-icon.png] Are elevated levels of IGF-1 caused by coronary arteriesoclerosis?: Molecular and clinical analysis.


[PMID 22354904] Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.


[PMID 22689104] No Effect of the IGF-1 Gene rs35767 and rs17032362 Polymorphisms in the Etiology of Idiopathic Short Stature.


GET Evidence
rs35767
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.726562
summary



[PMID 23757194] Functional Interaction between SNPs and Microsatellite in the Transcriptional Regulation of Insulin-Like Growth Factor 1


[PMID 23800627] Associations of IGF-1 gene variants and milk protein intake with IGF-I concentrations in infants at age 6 months - results from a randomized clinical trial.


[PMID 25724697] Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population


[PMID 25785549] The Uyghur Population and Genetic Susceptibility to Type 2 Diabetes: Potential Role for Variants in CDKAL1, JAZF1, and IGF1 Genes