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rs361072

From SNPedia

Orientationplus
Stabilizedplus
Make rs361072(A;A)
Make rs361072(A;G)
Make rs361072(G;G)
ReferenceGRCh38 38.1/141
Chromosome3
Position138759702
GenePIK3CB
is asnp
is mentioned by
dbSNPrs361072
ebirs361072
HLIrs361072
Exacrs361072
Varsomers361072
Maprs361072
PheGenIrs361072
hapmaprs361072
1000 genomesrs361072
hgdprs361072
ensemblrs361072
gopubmedrs361072
geneviewrs361072
scholarrs361072
googlers361072
pharmgkbrs361072
gwascentralrs361072
openSNPrs361072
23andMers361072
23andMe allrs361072
SNP Nexus

SNPshotrs361072
SNPdbers361072
MSV3drs361072
GWAS Ctlgrs361072
GMAF0.2984
Max Magnitude
? (A;A) (A;G) (G;G) 28
OMIM602925
DescPHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, BETA; PIK3CB
Variant
Relatedalso

[PMID 17971428] A single-nucleotide polymorphism in the p110beta gene promoter is associated with partial protection from insulin resistance in severely obese adolescents.

[PMID 17977952] Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.

[PMID 18398029] Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels.

[PMID 18772892OA-icon.png] Can genes for mammographic density inform cancer aetiology?

[PMID 19097921] In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes.

[PMID 20107106OA-icon.png] Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle.


[PMID 24114431] SNPs within the GH signaling pathway are associated with the early IGF-I response to GH replacement therapy in GHD adults