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rs3731566

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;G) 0 normal
(G;G) higher BP if rs4961(T) carrier
ReferenceGRCh38 38.1/142
Chromosome10
Position110126331
GeneADD3
is asnp
is mentioned by
dbSNPrs3731566
ebirs3731566
HLIrs3731566
Exacrs3731566
Varsomers3731566
Maprs3731566
PheGenIrs3731566
hapmaprs3731566
1000 genomesrs3731566
hgdprs3731566
ensemblrs3731566
gopubmedrs3731566
geneviewrs3731566
scholarrs3731566
googlers3731566
pharmgkbrs3731566
gwascentralrs3731566
openSNPrs3731566
23andMers3731566
23andMe allrs3731566
SNP Nexus

SNPshotrs3731566
SNPdbers3731566
MSV3drs3731566
GWAS Ctlgrs3731566
GMAF0.1878
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs3731566 is a SNP in the adducin 3 ADD3 gene. This variation on its own has not been linked to hypertension.

However, carriers of a rs4961(T) SNP (a SNP in the ADD1 gene) who also happen to be rs3731566(G;G) homozgyotes are found to have higher blood pressure (by about 8 mmHg) than if they are carriers of one or more rs3731566(A) alleles.[PMID 15716695]


[PMID 18787518] Arterial properties in relation to genetic variations in the adducin subunits in a white population.