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rs3736265

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs3736265(A;A)
Make rs3736265(A;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position23813084
GenePPARGC1A
is asnp
is mentioned by
dbSNPrs3736265
ebirs3736265
HLIrs3736265
Exacrs3736265
Varsomers3736265
Maprs3736265
PheGenIrs3736265
hapmaprs3736265
1000 genomesrs3736265
hgdprs3736265
ensemblrs3736265
gopubmedrs3736265
geneviewrs3736265
scholarrs3736265
googlers3736265
pharmgkbrs3736265
gwascentralrs3736265
openSNPrs3736265
23andMers3736265
23andMe allrs3736265
SNP Nexus

SNPshotrs3736265
SNPdbers3736265
MSV3drs3736265
GWAS Ctlgrs3736265
GMAF0.1088
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 19828207] Evaluation of the association between the PPARGC1A genetic polymorphisms and type 2 diabetes in Han Chinese population


[PMID 16642433OA-icon.png] Polymorphism in maternal LRP8 gene is associated with fetal growth.


[PMID 17187763] Analysis of PGC-1alpha variants Gly482Ser and Thr612Met concerning their PPARgamma2-coactivation function.


[PMID 18162502OA-icon.png] PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study.


[PMID 18588668OA-icon.png] Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).


[PMID 18599530OA-icon.png] Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.


[PMID 19133136OA-icon.png] The gene coding for PGC-1alpha modifies age at onset in Huntington's Disease.


[PMID 20426853OA-icon.png] Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function.


GET Evidence
PPARGC1A-T612M
aa_change Thr612Met
aa_change_short T612M
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0576315
summary



[PMID 23741228OA-icon.png] Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia


[PMID 24383721OA-icon.png] A single nucleotide polymorphism in the coding region of PGC-1alpha is a male-specific modifier of Huntington disease age-at-onset in a large European cohort