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rs3738414

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.6 0.4x decreased risk of breast cancer
(A;G) normal
(G;G) 0 normal
ReferenceGRCh38 38.1/141
Chromosome1
Position117210906
GeneVTCN1
is asnp
is mentioned by
dbSNPrs3738414
ebirs3738414
HLIrs3738414
Exacrs3738414
Varsomers3738414
Maprs3738414
PheGenIrs3738414
hapmaprs3738414
1000 genomesrs3738414
hgdprs3738414
ensemblrs3738414
gopubmedrs3738414
geneviewrs3738414
scholarrs3738414
googlers3738414
pharmgkbrs3738414
gwascentralrs3738414
openSNPrs3738414
23andMers3738414
23andMe allrs3738414
SNP Nexus

SNPshotrs3738414
SNPdbers3738414
MSV3drs3738414
GWAS Ctlgrs3738414
GMAF0.0854
Max Magnitude1.6
? (A;A) (A;G) (G;G) 28
rs3738414 is a SNP in the V-set domain containing T cell activation inhibitor 1 VTCN1 gene, which is also known as B7-H4.

A study of 500 Chinese Han women with breast cancer (and an equal number of matched controls) concluded that the rs3738414(A;A) genotype showed a significantly decreased risk of breast cancer (odds ratio 0.412, CI: 0.203-0.835).[PMID 19903360OA-icon.png]


[PMID 24125968] An investigation of the effects of FGFR2 and B7-H4 polymorphisms in breast cancer