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rs3740878

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1.2 1.46x type II diabetes risk; common
(A;G) 1.1 1.26x type II diabetes risk
Make rs3740878(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position44236252
GeneEXT2
is asnp
is mentioned by
dbSNPrs3740878
ebirs3740878
HLIrs3740878
Exacrs3740878
Varsomers3740878
Maprs3740878
PheGenIrs3740878
hapmaprs3740878
1000 genomesrs3740878
hgdprs3740878
ensemblrs3740878
gopubmedrs3740878
geneviewrs3740878
scholarrs3740878
googlers3740878
pharmgkbrs3740878
gwascentralrs3740878
openSNPrs3740878
23andMers3740878
23andMe allrs3740878
SNP Nexus

SNPshotrs3740878
SNPdbers3740878
MSV3drs3740878
GWAS Ctlgrs3740878
GMAF0.2874
Max Magnitude1.2
? (A;A) (A;G) (G;G) 28
rs3740878 increases susceptibility to Type II Diabetes 1.26 times for heterozygotes (AG) and 1.46 times for homozygotes (AA) [PMID 17293876]


[PMID 17786204OA-icon.png] Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.


[PMID 18443202OA-icon.png] Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.


[PMID 18461161OA-icon.png] Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.


[PMID 18544707OA-icon.png] Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.


[PMID 18556337OA-icon.png] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).


[PMID 18633108OA-icon.png] Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.


[PMID 18689899OA-icon.png] Exchangeable models of complex inherited diseases.


[PMID 19008344OA-icon.png] Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.


[PMID 19401414OA-icon.png] Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.


[PMID 21278902OA-icon.png] Genetic risk profiling for prediction of type 2 diabetes.


[PMID 22377712] Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.


[PMID 23052945] Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis


[PMID 25207843] Impact of variants of the EXT2 gene on Type 2 diabetes and its related traits in the Chinese han population