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rs3750848

From SNPedia

Orientationminus
Stabilizedminus
Make rs3750848(A;A)
Make rs3750848(A;C)
Make rs3750848(C;C)
ReferenceGRCh38 38.1/142
Chromosome10
Position122455799
GeneARMS2
is asnp
is mentioned by
dbSNPrs3750848
ebirs3750848
HLIrs3750848
Exacrs3750848
Varsomers3750848
Maprs3750848
PheGenIrs3750848
hapmaprs3750848
1000 genomesrs3750848
hgdprs3750848
ensemblrs3750848
gopubmedrs3750848
geneviewrs3750848
scholarrs3750848
googlers3750848
pharmgkbrs3750848
gwascentralrs3750848
openSNPrs3750848
23andMers3750848
23andMe allrs3750848
SNP Nexus

SNPshotrs3750848
SNPdbers3750848
MSV3drs3750848
GWAS Ctlgrs3750848
GMAF0.2736
Max Magnitude
? (A;A) (A;C) (C;C) 28
nature age related macular degeneration is associated with five highly correlated SNPs (rs10490924, rs3750848, rs3793917, rs11200638 and rs932275; r2 < 0.88) showed strongest association with AMD (2.72 < OR < 2.86)


[PMID 19933195] Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10q26


[PMID 21878851] ASSOCIATION BETWEEN HIGH-RISK DISEASE LOCI AND RESPONSE TO ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR TREATMENT FOR WET AGE-RELATED MACULAR DEGENERATION

[PMID 16642439OA-icon.png] Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.

[PMID 17884985OA-icon.png] A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.

[PMID 20140183OA-icon.png] Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration.

[PMID 20157352OA-icon.png] Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population.

GWAS snp
PMID [PMID 23577725OA-icon.png]
Trait Age-related macular degeneration (extreme sampling)
Title Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.
Risk Allele C
P-val 3E-29
Odds Ratio 3.12 [2.55-3.80]