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rs3751812

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) normal
(G;T) None
(T;T) increased risk of obesity
ReferenceGRCh38 38.1/141
Chromosome16
Position53784548
GeneFTO
is asnp
is mentioned by
dbSNPrs3751812
ebirs3751812
HLIrs3751812
Exacrs3751812
Varsomers3751812
Maprs3751812
PheGenIrs3751812
hapmaprs3751812
1000 genomesrs3751812
hgdprs3751812
ensemblrs3751812
gopubmedrs3751812
geneviewrs3751812
scholarrs3751812
googlers3751812
pharmgkbrs3751812
gwascentralrs3751812
openSNPrs3751812
23andMers3751812
23andMe allrs3751812
SNP Nexus

SNPshotrs3751812
SNPdbers3751812
MSV3drs3751812
GWAS Ctlgrs3751812
GMAF0.242
Max Magnitude
? (G;G) (G;T) (T;T) 28
Within the FTO gene, many SNPs appear to be co-inherited. The SNP showing the strongest association with body weight (i.e. body mass index, BMI) is not rs3751812, although this SNP is one of the co-inherited SNPs in the FTO gene region. For more information, refer to the FTO gene or the most studied FTO SNPs, rs9930506 or rs9939609. [PMID 17658951OA-icon.png]

23andMe considers rs3751812(T) equivalent to the rs9939609(A)

[PMID 18335027OA-icon.png] implicated for african americans

Neighborrs9923233
Distance738
[PMID 19322589OA-icon.png] Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study


[PMID 20430937OA-icon.png] Fine-mapping of the association with obesity at the FTO locus in African-derived populations


[PMID 21443588] Association between the FTO gene and overweight in Japanese children and adolescents


[PMID 18379722OA-icon.png] Variations in the FTO gene are associated with severe obesity in the Japanese.


[PMID 18647953OA-icon.png] Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.


[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.


[PMID 19074959OA-icon.png] ATOM: a powerful gene-based association test by combining optimally weighted markers.


[PMID 19265514OA-icon.png] FTO gene variation and measures of body mass in an African population.


[PMID 19478790OA-icon.png] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.


[PMID 20381893OA-icon.png] The genetics of obesity: FTO leads the way.


[PMID 20404173OA-icon.png] A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.


[PMID 20442772OA-icon.png] Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.


[PMID 20502638OA-icon.png] Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.


[PMID 20694148OA-icon.png] A genome-wide association study of the metabolic syndrome in Indian Asian men.


[PMID 21102551OA-icon.png] Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.


[PMID 23628854OA-icon.png] FTO predicts weight regain in the Look AHEAD clinical trial


[PMID 23933215] Body Mass Index, but not FTO genotype or Major Depressive Disorder, influences brain structure


[PMID 23408508OA-icon.png] Obesity-susceptibility loci and the tails of the pediatric BMI distribution


[PMID 21799482OA-icon.png] Common genetic variants and central adiposity among Asian-Indians.


[PMID 24911064OA-icon.png] Association of FTO Polymorphisms with Obesity and Metabolic Parameters in Han Chinese Adolescents


[PMID 26726774] Gender-Dependent Association of FTO Polymorphisms with Body Mass Index in Mexicans.