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rs3752246

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common on affy axiom data
Make rs3752246(C;G)
Make rs3752246(G;G)
ReferenceGRCh38 38.1/141
Chromosome19
Position1056493
GeneABCA7
is asnp
is mentioned by
dbSNPrs3752246
ebirs3752246
HLIrs3752246
Exacrs3752246
Varsomers3752246
Maprs3752246
PheGenIrs3752246
hapmaprs3752246
1000 genomesrs3752246
hgdprs3752246
ensemblrs3752246
gopubmedrs3752246
geneviewrs3752246
scholarrs3752246
googlers3752246
pharmgkbrs3752246
gwascentralrs3752246
openSNPrs3752246
23andMers3752246
23andMe allrs3752246
SNP Nexus

SNPshotrs3752246
SNPdbers3752246
MSV3drs3752246
GWAS Ctlgrs3752246
GMAF0.1763
Max Magnitude0
? (C;C) (C;G) (G;G) 28
GWAS snp
PMID [PMID 21460841OA-icon.png]
Trait
Title Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Risk Allele G
P-val 6E-7
Odds Ratio 1.1500 [1.09-1.21]


GET Evidence
ABCA7-G1527A
aa_change Gly1527Ala
aa_change_short G1527A
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.872908
summary



[PMID 23556446] Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease


[PMID 23669301OA-icon.png] Interaction between two cholesterol metabolism genes influences memory: findings from the Wisconsin Registry for Alzheimer's Prevention.


[PMID 26141617] Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study