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rs3753380

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs3753380(A;G)
Make rs3753380(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position78490747
GenePTGFR
is asnp
is mentioned by
dbSNPrs3753380
ebirs3753380
HLIrs3753380
Exacrs3753380
Varsomers3753380
Maprs3753380
PheGenIrs3753380
hapmaprs3753380
1000 genomesrs3753380
hgdprs3753380
ensemblrs3753380
gopubmedrs3753380
geneviewrs3753380
scholarrs3753380
googlers3753380
pharmgkbrs3753380
gwascentralrs3753380
openSNPrs3753380
23andMers3753380
23andMe allrs3753380
SNP Nexus

SNPshotrs3753380
SNPdbers3753380
MSV3drs3753380
GWAS Ctlgrs3753380
GMAF0.241
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 22060278OA-icon.png] Lack of association between polymorphisms in the prostaglandin F(2alpha) receptor and solute carrier organic anion transporter family 2A1 genes and intraocular pressure response to prostaglandin analogs.


GET Evidence
rs3753380
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.796875
summary



[PMID 24457363] Association between genetic polymorphisms of the prostaglandin F2α receptor gene, and response to latanoprost in patients with glaucoma and ocular hypertension


[PMID 25704319] Association between SNPs of Metalloproteinases and Prostaglandin F2α Receptor Genes and Latanoprost Response in Open-Angle Glaucoma


ClinVar
Risk rs3753380(G;G)
Alt rs3753380(G;G)
Reference rs3753380(A;A)
Significance Drug-response
Disease latanoprost response - Efficacy
Variation info
Gene PTGFR
CLNDBN latanoprost response - Efficacy
Reversed 1
HGVS NC_000001.10:g.78956432T>C
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211367.1,