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rs3758149

From SNPedia

Orientationminus
Stabilizedminus
Make rs3758149(C;C)
Make rs3758149(C;T)
Make rs3758149(T;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position63039169
GeneGGH
is asnp
is mentioned by
dbSNPrs3758149
ebirs3758149
HLIrs3758149
Exacrs3758149
Varsomers3758149
Maprs3758149
PheGenIrs3758149
hapmaprs3758149
1000 genomesrs3758149
hgdprs3758149
ensemblrs3758149
gopubmedrs3758149
geneviewrs3758149
scholarrs3758149
googlers3758149
pharmgkbrs3758149
gwascentralrs3758149
openSNPrs3758149
23andMers3758149
23andMe allrs3758149
SNP Nexus

SNPshotrs3758149
SNPdbers3758149
MSV3drs3758149
GWAS Ctlgrs3758149
GMAF0.2337
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 22018726OA-icon.png] Genetic variation in folylpolyglutamate synthase and gamma-glutamyl hydrolase and plasma homocysteine levels in the Singapore Chinese Health Study

[PMID 16826517OA-icon.png] Epigenetic regulation of human gamma-glutamyl hydrolase activity in acute lymphoblastic leukemia cells.


[PMID 18842806OA-icon.png] Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.


GET Evidence
rs3758149
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.28125
summary



[PMID 24908438] Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia


[PMID 27566582] Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma.