Have questions? Visit https://www.reddit.com/r/SNPedia

rs3765524

From SNPedia

Orientationplus
Stabilizedplus
Make rs3765524(C;C)
Make rs3765524(C;T)
Make rs3765524(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position94298541
GenePLCE1
is asnp
is mentioned by
dbSNPrs3765524
ebirs3765524
HLIrs3765524
Exacrs3765524
Varsomers3765524
Maprs3765524
PheGenIrs3765524
hapmaprs3765524
1000 genomesrs3765524
hgdprs3765524
ensemblrs3765524
gopubmedrs3765524
geneviewrs3765524
scholarrs3765524
googlers3765524
pharmgkbrs3765524
gwascentralrs3765524
openSNPrs3765524
23andMers3765524
23andMe allrs3765524
SNP Nexus

SNPshotrs3765524
SNPdbers3765524
MSV3drs3765524
GWAS Ctlgrs3765524
GMAF0.281
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20729852OA-icon.png]
Trait
Title A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
Risk Allele T
P-val 2E-9
Odds Ratio 1.35 [1.22-1.49]
OMIM133239
Desc
Variant
Relatedalso
GWAS snp
PMID [PMID 22001756OA-icon.png]
Trait
Title Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.
Risk Allele
P-val 3E-10
Odds Ratio 1.2500 None


GET Evidence
PLCE1-T1777I
aa_change Thr1777Ile
aa_change_short T1777I
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.32145
summary



[PMID 22740136] Association of 10q23 with colorectal cancer in a Chinese population.


[PMID 24935391] Phospholipase C Epsilon 1 (PLCE1 rs2274223A>G, rs3765524C>T and rs7922612C>T) Polymorphisms and Esophageal Cancer Risk in the Kashmir Valley


[PMID 25139097] Role of novel and GWAS originated PLCE1 genetic variants in susceptibility and prognosis of esophageal cancer patients in northern Indian population


[PMID 25992311OA-icon.png] Genetic variants and risk of gastric cancer: a pathway analysis of a genome-wide association study


[PMID 26554163] Genetic Variation of BCL2 (rs2279115), NEIL2 (rs804270), LTA (rs909253), PSCA (rs2294008) and PLCE1 (rs3765524, rs10509670) Genes and Their Correlation to Gastric Cancer Risk Based on Universal Tagged Arrays and Fe3O4 Magnetic Nanoparticles