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rs3765598

From SNPedia

Orientationplus
Stabilizedplus
Make rs3765598(C;C)
Make rs3765598(C;T)
Make rs3765598(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position113851841
GenePTPN22, RP5-1073O3.2
is asnp
is mentioned by
dbSNPrs3765598
ebirs3765598
HLIrs3765598
Exacrs3765598
Varsomers3765598
Maprs3765598
PheGenIrs3765598
hapmaprs3765598
1000 genomesrs3765598
hgdprs3765598
ensemblrs3765598
gopubmedrs3765598
geneviewrs3765598
scholarrs3765598
googlers3765598
pharmgkbrs3765598
gwascentralrs3765598
openSNPrs3765598
23andMers3765598
23andMe allrs3765598
SNP Nexus

SNPshotrs3765598
SNPdbers3765598
MSV3drs3765598
GWAS Ctlgrs3765598
GMAF0.1593
Max Magnitude
? (C;C) (C;T) (T;T) 28
Rs3765598
PubMed [PMID 16175503OA-icon.png]
Affy Probeset SNP_A-1962697
Affy Orientation same
On GW 5.0 1
Alleles A/B C/T
Ancestral C
Population Caucasian
Allele T
Case Freq. 0.21
Control Freq. 0.16
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 1.40
Disease Rheumatoid Arthritis (RA)


rs3765598 is in linkage disequilibrium with a polymorphism that increases susceptibility to Rheumatoid Arthritis 1.40 times for carriers of the T allele [PMID 16175503OA-icon.png]


[PMID 19180477OA-icon.png] Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.


[PMID 19956096OA-icon.png] rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 23950893OA-icon.png] PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes