|?|| (A;A) (A;G) (G;G) ||28|
This SNP is located on chromosome 2q22-23, in the activin receptor type 2 gene (ACVR2A
A study of 1139 Norwegian women with one or more pre-eclamptic pregnancies and 2269 controls (women with normal pregnancies) identified four SNPs in this region (rs1424941, rs1014064, rs2161983 and rs3768687) as associated with higher risk for pre-eclampsia.
[PMID 18781190] Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study).
[PMID 19126782] Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia.