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rs3775291(A;A)

From SNPedia

0.44x decreased risk for dry age related macular degeneration
Is agenotype
ofrs3775291
GeneTLR3
Chromosome4
Position186,082,920
mentionedby
Magnitude2.2
ReputeGood
Geno Mag Summary
(A;A) 2.2 0.44x decreased risk for dry age related macular degeneration
(A;G) 2.1 0.71x decreased risk for dry age related macular degeneration
(G;G) 2 common but higher risk of age related macular degeneration

Some association has been reported between polymorphisms in TLR genes and age related macular degeneration(ARMD). However, these variants are not likely to have a major impact of the overall risk of developing macular degeneration.

[PMID 18385087]