Have questions? Visit https://www.reddit.com/r/SNPedia

rs3783799

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1.4x increased risk for stroke
(A;G) 1.4x increased risk for stroke
(G;G) 0 normal risk
ReferenceGRCh38 38.1/141
Chromosome14
Position61452498
GenePRKCH
is asnp
is mentioned by
dbSNPrs3783799
ebirs3783799
HLIrs3783799
Exacrs3783799
Varsomers3783799
Maprs3783799
PheGenIrs3783799
hapmaprs3783799
1000 genomesrs3783799
hgdprs3783799
ensemblrs3783799
gopubmedrs3783799
geneviewrs3783799
scholarrs3783799
googlers3783799
pharmgkbrs3783799
gwascentralrs3783799
openSNPrs3783799
23andMers3783799
23andMe allrs3783799
SNP Nexus

SNPshotrs3783799
SNPdbers3783799
MSV3drs3783799
GWAS Ctlgrs3783799
GMAF0.0629
Max Magnitude0
? (A;A) (A;G) (G;G) 28
A common SNP only in Asian populations, this SNP and a close neighbor also in PRKCH gene, rs3783799, have been associated with higher risk for subcortical silent brain infarction, a common form of stroke.

The odds ratio for carriers of a risk allele is 1.27 (CI: 1.09-1.48, p=0.0026) compared to individuals homozygous for the non-risk allele, based on studies of ~300 Japanese patients. [PMID 18164711]


[PMID 20602195] PRKCH gene polymorphism is associated with the risk of severe gastric atrophy

[PMID 19703523] Association of PRKCH gene with lacunar infarction in a local Chinese Han population.