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rs3796530

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs3796530(C;T)
Make rs3796530(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position56931087
GeneREST
is asnp
is mentioned by
dbSNPrs3796530
ebirs3796530
HLIrs3796530
Exacrs3796530
Varsomers3796530
Maprs3796530
PheGenIrs3796530
hapmaprs3796530
1000 genomesrs3796530
hgdprs3796530
ensemblrs3796530
gopubmedrs3796530
geneviewrs3796530
scholarrs3796530
googlers3796530
pharmgkbrs3796530
gwascentralrs3796530
openSNPrs3796530
23andMers3796530
23andMe allrs3796530
SNP Nexus

SNPshotrs3796530
SNPdbers3796530
MSV3drs3796530
GWAS Ctlgrs3796530
GMAF0.06612
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 18518926] - rs2227902 and rs3796530 were found to be in 100% LD with a VNTR length variant in the REST gene in a sample of 746 elderly Caucasians. Minor alleles (T and A, respectively) at both locations associated with the 4-length VNTR, while common alleles associated with the VNTR 5-length repeat. Carriers of the 4-length VNTR homozygous for the Val66 variant in the BDNF gene performed slightly, but significantly (p = 0.004), better than those without in the general cognitive tests performed in the study. Carriers of the 5-length VNTR and the 66Met BDNF variant had significantly lower g (p = 0.01), but the effect was not as great as the individual effect of the 66Met allele.