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rs3800373

From SNPedia

Orientationminus
Stabilizedminus
Make rs3800373(G;G)
Make rs3800373(G;T)
Make rs3800373(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position35574699
GeneFKBP5, LOC101929309
is asnp
is mentioned by
dbSNPrs3800373
ebirs3800373
HLIrs3800373
Exacrs3800373
Varsomers3800373
Maprs3800373
PheGenIrs3800373
hapmaprs3800373
1000 genomesrs3800373
hgdprs3800373
ensemblrs3800373
gopubmedrs3800373
geneviewrs3800373
scholarrs3800373
googlers3800373
pharmgkbrs3800373
gwascentralrs3800373
openSNPrs3800373
23andMers3800373
23andMe allrs3800373
SNP Nexus

SNPshotrs3800373
SNPdbers3800373
MSV3drs3800373
GWAS Ctlgrs3800373
GMAF0.2971
Max Magnitude
? (G;G) (G;T) (T;T) 28
[PMID 18349090OA-icon.png] rs9296158 rs3800373 rs1360780 rs9470080 linked with the severity of child abuse to predict level of adult PTSD symptoms after correcting for multiple testing.


[PMID 19199039OA-icon.png] Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder



[PMID 20090668OA-icon.png] Interaction of FKBP5, a Stress-Related Gene, with Childhood Trauma Increases the Risk for Attempting Suicide


[PMID 20008943OA-icon.png] Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study


[PMID 20393453OA-icon.png] Interaction of FKBP5 with Childhood Adversity on Risk for Post-Traumatic Stress Disorder

[PMID 20709156] Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders


[PMID 22134958] Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients


[PMID 15637659OA-icon.png] Linkage disequilibrium patterns and tagSNP transferability among European populations.


[PMID 17081296OA-icon.png] Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits.


[PMID 18191112OA-icon.png] The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort.


[PMID 19455174OA-icon.png] Psychobiology and molecular genetics of resilience.


[PMID 19676097OA-icon.png] FKBP5 polymorphisms and antidepressant response in geriatric depression.


[PMID 19750552OA-icon.png] Risk and resilience: genetic and environmental influences on development of the stress response.


[PMID 20726698OA-icon.png] Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals.


[PMID 21112363] Association of FKBP5 gene haplotypes with completed suicide in the Japanese population.


[PMID 21172166OA-icon.png] Pharmacogenetics of antidepressant response.


[PMID 21448414OA-icon.png] Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease.


[PMID 21788965] Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms.


[PMID 21978546OA-icon.png] Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.


[PMID 22213790OA-icon.png] Interaction between FKBP5 and childhood trauma and risk of aggressive behavior.


[PMID 22979952OA-icon.png] FKBP5 AND EMOTIONAL NEGLECT INTERACT TO PREDICT INDIVIDUAL DIFFERENCES IN AMYGDALA REACTIVITY


GET Evidence
rs3800373
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.648438
summary



[PMID 23062294OA-icon.png] The role of limbic system irritability in linking history of childhood maltreatment and psychiatric outcomes in low-income, high-risk women: moderation by FK506 binding protein 5 haplotype.


[PMID 23733030] Pharmacogenetics in major depression: a comprehensive meta-analysis.


[PMID 24845178OA-icon.png] Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype


[PMID 24856550] FKBP5 polymorphism is associated with major depression but not with bipolar disorder


[PMID 27078785] FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study


[PMID 27648526] The influence of FKBP5 genotype on expression of FKBP5 and other glucocorticoid-regulated genes, dependent on trauma exposure.