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rs3804100

From SNPedia

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Geno Mag Summary
(C;C) somwhat increased risk for type-1 diabetes and allergic asthma
(C;T) somewhat increased risk for type-1 diabetes and allergic asthma
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome4
Position153704257
GeneTLR2
is asnp
is mentioned by
dbSNPrs3804100
ebirs3804100
HLIrs3804100
Exacrs3804100
Varsomers3804100
Maprs3804100
PheGenIrs3804100
hapmaprs3804100
1000 genomesrs3804100
hgdprs3804100
ensemblrs3804100
gopubmedrs3804100
geneviewrs3804100
scholarrs3804100
googlers3804100
pharmgkbrs3804100
gwascentralrs3804100
openSNPrs3804100
23andMers3804100
23andMe allrs3804100
SNP Nexus

SNPshotrs3804100
SNPdbers3804100
MSV3drs3804100
GWAS Ctlgrs3804100
GMAF0.1157
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs3804100, also known as 1350T/C, is a SNP in the toll-like receptor 2 TLR2 gene.

A study of 700 T1D children, 357 nuclear families with T1D children and 796 children from the 'Environment and Childhood Asthma' study concluded that both type-1 diabetes and allergic asthma were significantly associated with the rs3804100(T) allele.[PMID 19148143]


[PMID 22235236OA-icon.png] Toll-like receptor 2 gene polymorphisms associated with aggressive periodontitis in Japanese


[PMID 22309608OA-icon.png] The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility


[PMID 18325643OA-icon.png] Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.


[PMID 18396467OA-icon.png] Genetic variation and haplotype structures of innate immunity genes in eastern India.


[PMID 18556337OA-icon.png] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).


[PMID 19029192OA-icon.png] A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.


[PMID 19505919OA-icon.png] Toll-like receptor signaling pathway variants and prostate cancer mortality.


[PMID 19543401OA-icon.png] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.


[PMID 20057905OA-icon.png] Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma.


[PMID 20113509OA-icon.png] Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts.


[PMID 20463618OA-icon.png] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.


[PMID 21111021] Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.


[PMID 21424379OA-icon.png] The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity.


[PMID 21437199OA-icon.png] Toll-like receptor 2 (TLR2) gene polymorphisms are not associated with sarcoidosis in the Japanese population.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.


[PMID 21887520] Association of toll-like receptor 2 polymorphisms with National Institute of Health Stroke Scale scores of ischemic stroke patients.


[PMID 23484049OA-icon.png] Genetic Polymorphisms in Toll-Like Receptors among Pediatric Patients with Renal Parenchymal Infections of Different Clinical Severities


[PMID 23166414OA-icon.png] Association of Toll-like receptor 2 polymorphisms with papillary thyroid cancer and clinicopathologic features in a Korean population


[PMID 23906542] Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection but not with congenital CMV disease


[PMID 25928077OA-icon.png] Screening toll-like receptor markers to predict latent tuberculosis infection and subsequent tuberculosis disease in a Chinese population