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rs3825942(T;T)

From SNPedia

10x to 27x lower risk of exfoliation glaucoma
Is agenotype
ofrs3825942
GeneLOXL1, RNASEH2B, LOXL1-AS1
Chromosome15
Position73,927,241
mentionedby
Magnitude2.5
ReputeGood
Geno Mag Summary
(C;C) 2.3 common but 10x higher glaucoma risk in most (but not all) populations
(C;T) 1.8 possibly lower glaucoma risk
(T;T) 2.5 10x to 27x lower risk of exfoliation glaucoma

Unless you are a black south African, this uncommon SNP drastically reduces your risk of exfoliation glaucoma (also known as exfoliation syndrome, or pseudoexfoliation syndrome PEX). That form of glaucoma causes up to 10% of the cases of blindness in many countries, including the US. [PMID 17690259] This mutation may not protect you from other kinds of glaucoma though.[PMID 20142848]