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] Association of alcohol dehydrogenase polymorphisms and lifestyle factors with excessive alcohol intake within the Spanish population (EPIC-Spain)
A study of 653 Spanish heavy drinkers compared to 880 controls found ADH6 gene rs3857224(T) was associated with heavy alcohol intake in women (odds ratio 1.61, CI: 1.21–2.14, p = 10e−3), but not in men.
[PMID 18331377] Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.
[PMID 19193628] ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.
[PMID 19247474] Genome-wide and candidate gene association study of cigarette smoking behaviors.
[PMID 19298322] Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans.