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rs3889728

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) increased risk for preeclampsia
(A;G) increased risk for preeclamppsia
(G;G) normal risk
ReferenceGRCh38 38.1/141
Chromosome1
Position230713085
GeneAGT
is asnp
is mentioned by
dbSNPrs3889728
ebirs3889728
HLIrs3889728
Exacrs3889728
Varsomers3889728
Maprs3889728
PheGenIrs3889728
hapmaprs3889728
1000 genomesrs3889728
hgdprs3889728
ensemblrs3889728
gopubmedrs3889728
geneviewrs3889728
scholarrs3889728
googlers3889728
pharmgkbrs3889728
gwascentralrs3889728
openSNPrs3889728
23andMers3889728
23andMe allrs3889728
SNP Nexus

SNPshotrs3889728
SNPdbers3889728
MSV3drs3889728
GWAS Ctlgrs3889728
GMAF0.3104
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs3889728 is a SNP in the AGT gene that, at least when part of a haplotype, has been associated with increased risk for developing pre-eclampsia, but it was not reported to have the most influence of the 3 SNPs in the haplotype. The 2.1 fold increased risk (CI: 1.4-3.4, p=0.0008) for pre-eclampsia was reported for haplotype rs3889728(A)-rs4762(T)-rs699(C).[PMID 14638622]


[PMID 24978482] Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: Interplay with hypertension and intakes of sodium, potassium and fluid