Have questions? Visit https://www.reddit.com/r/SNPedia

rs393152

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.5 Increased risk of both PD and AD
(A;G) 1.2 Slight increased risk of both PD and AD
(G;G) 1.3 Normal risk of both PD and AD
ReferenceGRCh38 38.1/141
Chromosome17
Position45641777
GeneCRHR1, C17orf69
is asnp
is mentioned by
dbSNPrs393152
ebirs393152
HLIrs393152
Exacrs393152
Varsomers393152
Maprs393152
PheGenIrs393152
hapmaprs393152
1000 genomesrs393152
hgdprs393152
ensemblrs393152
gopubmedrs393152
geneviewrs393152
scholarrs393152
googlers393152
pharmgkbrs393152
gwascentralrs393152
openSNPrs393152
23andMers393152
23andMe allrs393152
SNP Nexus

SNPshotrs393152
SNPdbers393152
MSV3drs393152
GWAS Ctlgrs393152
GMAF0.2369
Max Magnitude1.5
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19915575OA-icon.png]
Trait Parkinson's disease
Title Genome-wide association study reveals genetic risk underlying Parkinson's disease
Risk Allele G
P-val 2E-16
Odds Ratio 1.30 [NR]
OMIM600274
Desc
Variant
Relatedalso
OMIM613164
Desc
Variant
Relatedalso
[PMID 18985386OA-icon.png] Genomewide association study for susceptibility genes contributing to familial Parkinson disease.


[PMID 20070850OA-icon.png] Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.


[PMID 21898123] The age at motor symptoms onset in LRRK2-associated Parkinson's disease is affected by a variation in the MAPT locus: a possible interaction.


[PMID 25687773] Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.


GET Evidence
rs393152
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.325397
summary