|?|| (C;C) (C;T) (T;T) ||28|
associated with genetic susceptibility to tuberculosis in West Africa
|Desc||MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO|
[PMID 21033425] [Study on relation between Sp110 gene polymorphism and tuberculosis genetic susceptibility of Chongqing Han People]
[PMID 16803959] Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.
[PMID 20196868] Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis.
[PMID 22691368] SP110 gene polymorphisms and tuberculosis susceptibility: A systematic review and meta-analysis based on 10 624 subjects.
|| Low clinical importance, Uncertain pathogenic
|| This variant is associated with a slightly increased risk of tuberculosis. It is unclear whether it is itself causal, or in linkage disequilibrium with some other causal variant that has a stronger effect.
[PMID 22522001] Polymorphisms in SP110 are not associated with pulmonary tuberculosis in Indonesians