rs397515635

plus

Geno	Mag	Summary
(-;-)	0	common/normal
(-;CAAC)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TTAT)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs397515635(-;TTAG)

Make rs397515635(TTAG;TTAG)

Reference

GRCh38.p2 38.2/147

Chromosome

13

Position

32332667

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs397515635
dbSNP (classic)	rs397515635
ClinGen	rs397515635
ebi	rs397515635
HLI	rs397515635
Exac	rs397515635
Gnomad	rs397515635
Varsome	rs397515635
LitVar	rs397515635
Map	rs397515635
PheGenI	rs397515635
Biobank	rs397515635
1000 genomes	rs397515635
hgdp	rs397515635
ensembl	rs397515635
geneview	rs397515635
scholar	rs397515635
google	rs397515635
pharmgkb	rs397515635
gwascentral	rs397515635
openSNP	rs397515635
23andMe	rs397515635
SNPshot	rs397515635
SNPdbe	rs397515635
MSV3d	rs397515635
GWAS Ctlg	rs397515635

Max Magnitude

6

aka c.1188_1189insTTAG (p.Gln397fs), c.1189_1190insTTAT (p.Gln397fs) and also c.1189_1190insTTAG (p.Gln397fs), all of which are considered pathogenic for breast cancer in ClinVar

Mentioned as a pathogenic/likely pathogenic mutation associated with cancer predisposition in [PMID 26681312 ]