|(C;C)||1.9||Common, but higher lung cancer risk ?|
|Title||Lung cancer susceptibility locus at 5p15.33|
|Odds Ratio||1.18 [1.12-1.24]|
[PMID 20056643] A rigorous and comprehensive validation: common genetic variations and lung cancer
[PMID 19465454] The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung
[PMID 21750227] Single-nucleotide polymorphisms (5p15.33, 15q25.1, 6p22.1, 6q27 and 7p15.3) and lung cancer survival in the European Prospective Investigation into Cancer and Nutrition (EPIC)
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[PMID 21966413] Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population
[PMID 19369581] Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population.
[PMID 19654303] Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
[PMID 19836008] A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
[PMID 20101243] A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
[PMID 20548021] Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.
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[PMID 21081471] Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study.
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[PMID 22228261] Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population.
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[PMID 22523397] Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis.
|qualified_impact||Insufficiently evaluated pathogenic|
[PMID 24194831] The SNP rs402710 in 5p15.33 Is Associated with Lung Cancer Risk: A Replication Study in Chinese Population and a Meta-Analysis
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