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rs4076128

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.8x increased breast cancer risk for women having high linoleic acid diets
(A;G) normal
(G;G) normal
ReferenceGRCh38 38.1/141
Chromosome13
Position30731006
GeneALOX5AP
is asnp
is mentioned by
dbSNPrs4076128
ebirs4076128
HLIrs4076128
Exacrs4076128
Varsomers4076128
Maprs4076128
PheGenIrs4076128
hapmaprs4076128
1000 genomesrs4076128
hgdprs4076128
ensemblrs4076128
gopubmedrs4076128
geneviewrs4076128
scholarrs4076128
googlers4076128
pharmgkbrs4076128
gwascentralrs4076128
openSNPrs4076128
23andMers4076128
23andMe allrs4076128
SNP Nexus

SNPshotrs4076128
SNPdbers4076128
MSV3drs4076128
GWAS Ctlgrs4076128
GMAF0.4183
Max Magnitude
? (A;A) (A;G) (G;G) 28
Based on a mixed-ethnicity study, women consuming a diet high in linoleic acid (top quartile of intake, >17.4 g/d) and carrying the rs4076128(A;A) genotype were associated with higher breast cancer risk (age- and race-adjusted odds ratio, 1.8, CI: 1.2-2.9) compared with (A;G) and (G;G) genotypes. Among women consuming </=17.4 g/d of linoleic acid, there was no association with breast cancer risk. [PMID 18843019]


[PMID 18366797OA-icon.png] Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.