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rs4085613

From SNPedia

Orientationminus
Stabilizedminus
Make rs4085613(A;A)
Make rs4085613(A;C)
Make rs4085613(C;C)
ReferenceGRCh38 38.1/141
Chromosome1
Position152577542
GeneLCE3D
is asnp
is mentioned by
dbSNPrs4085613
ebirs4085613
HLIrs4085613
Exacrs4085613
Varsomers4085613
Maprs4085613
PheGenIrs4085613
hapmaprs4085613
1000 genomesrs4085613
hgdprs4085613
ensemblrs4085613
gopubmedrs4085613
geneviewrs4085613
scholarrs4085613
googlers4085613
pharmgkbrs4085613
gwascentralrs4085613
openSNPrs4085613
23andMers4085613
23andMe allrs4085613
SNP Nexus

SNPshotrs4085613
SNPdbers4085613
MSV3drs4085613
GWAS Ctlgrs4085613
GMAF0.4123
Max Magnitude
? (A;A) (A;C) (C;C) 28
rs4085613 is a SNP in the late cornified envelope 3D LCE3D gene cluster.

rs4085613 has been associated with psoriasis in a Chinese study involving 1,139 cases and 1,132 controls.[PMID 19169255]

See also: 23andMe blog psoriasis Chinese

  • rs4085613(G) 1.32x risk
OMIM603935
DescPSORIASIS SUSCEPTIBILITY 4; PSORS4
Variant
Relatedalso
[PMID 20643763OA-icon.png] Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis


[PMID 21628307] Deletion of LCE3C_LCE3B is associated with rheumatoid arthritis and systemic lupus erythematosus in the Chinese Han population


[PMID 19693967] [Enlightenment from genome-wide association study to genetics of psoriasis].


[PMID 20606885OA-icon.png] Genetics of psoriasis and psoriatic arthritis.


[PMID 21253569OA-icon.png] Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?


[PMID 21304891OA-icon.png] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.


GET Evidence
rs4085613
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.523438
summary