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rs4086116

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs4086116(C;T)
Make rs4086116(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position94947445
GeneCYP2C9
is asnp
is mentioned by
dbSNPrs4086116
ebirs4086116
HLIrs4086116
Exacrs4086116
Varsomers4086116
Maprs4086116
PheGenIrs4086116
hapmaprs4086116
1000 genomesrs4086116
hgdprs4086116
ensemblrs4086116
gopubmedrs4086116
geneviewrs4086116
scholarrs4086116
googlers4086116
pharmgkbrs4086116
gwascentralrs4086116
openSNPrs4086116
23andMers4086116
23andMe allrs4086116
SNP Nexus

SNPshotrs4086116
SNPdbers4086116
MSV3drs4086116
GWAS Ctlgrs4086116
GMAF0.168
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18535201OA-icon.png]
Trait Warfarin maintenance dose
Title A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
Risk Allele
P-val 6.0000000000000003E-12
Odds Ratio NR NR


[PMID 19578179] A genome-wide association study of acenocoumarol maintenance dosage.


GET Evidence
rs4086116
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.1875
summary



[PMID 23089684] Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates.