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rs4143832

From SNPedia

Orientationminus
Stabilizedminus
Make rs4143832(A;A)
Make rs4143832(A;C)
Make rs4143832(C;C)
ReferenceGRCh38 38.1/141
Chromosome5
Position132527285
is asnp
is mentioned by
dbSNPrs4143832
ebirs4143832
HLIrs4143832
Exacrs4143832
Varsomers4143832
Maprs4143832
PheGenIrs4143832
hapmaprs4143832
1000 genomesrs4143832
hgdprs4143832
ensemblrs4143832
gopubmedrs4143832
geneviewrs4143832
scholarrs4143832
googlers4143832
pharmgkbrs4143832
gwascentralrs4143832
openSNPrs4143832
23andMers4143832
23andMe allrs4143832
SNP Nexus

SNPshotrs4143832
SNPdbers4143832
MSV3drs4143832
GWAS Ctlgrs4143832
GMAF0.2002
Max Magnitude
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 19198610]
Trait Plasma eosinophil count
Title Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Risk Allele C
P-val 1E-10
Odds Ratio 7.10 [4.9-9.2] % standard unit increase
OMIM147850
DescINTERLEUKIN 5; IL5
Variant
Relatedalso
[PMID 18056382OA-icon.png] Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.

[PMID 18614543OA-icon.png] The 5q31 variants associated with psoriasis and Crohn's disease are distinct.

[PMID 19860791] Genetic evidence for a role of IL33 in nasal polyposis.


GET Evidence
rs4143832
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.78125
summary



[PMID 23328882] Meta-analyses of four eosinophil related gene variants in coronary heart disease.