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rs4151620

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;G)
Make rs4151620(C;C)
Make rs4151620(G;G)
ReferenceGRCh38 38.1/141
Chromosome13
Position48474923
GeneRB1
is asnp
is mentioned by
dbSNPrs4151620
ebirs4151620
HLIrs4151620
Exacrs4151620
Varsomers4151620
Maprs4151620
PheGenIrs4151620
hapmaprs4151620
1000 genomesrs4151620
hgdprs4151620
ensemblrs4151620
gopubmedrs4151620
geneviewrs4151620
scholarrs4151620
googlers4151620
pharmgkbrs4151620
gwascentralrs4151620
openSNPrs4151620
23andMers4151620
23andMe allrs4151620
SNP Nexus

SNPshotrs4151620
SNPdbers4151620
MSV3drs4151620
GWAS Ctlgrs4151620
GMAF0.1001
Max Magnitude
rs4151620(C;G) and rs4151620(G;G) are associated with a reduced risk of ovarian cancer compared with rs4151620(G;G) individuals.

This snp has been linked to ovarian cancer [PMID 17047088]

Intron 17 of RB1 contains the open reading frame for the P2RY5 gene, and rs4151620 is perfectly correlated with rs2227311, which is located in the 5'-untranslated region of P2RY5 and is predicted to affect P2RY5 transcription. rs2854344 has been reported previously to be associated with breast cancer risk [PMID 16685266OA-icon.png]


[PMID 18281541OA-icon.png] Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.


[PMID 19258477OA-icon.png] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.