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rs42041

From SNPedia

Orientationplus
Stabilizedplus
Make rs42041(C;C)
Make rs42041(C;G)
Make rs42041(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position92617430
GeneCDK6
is asnp
is mentioned by
dbSNPrs42041
ebirs42041
HLIrs42041
Exacrs42041
Varsomers42041
Maprs42041
PheGenIrs42041
hapmaprs42041
1000 genomesrs42041
hgdprs42041
ensemblrs42041
gopubmedrs42041
geneviewrs42041
scholarrs42041
googlers42041
pharmgkbrs42041
gwascentralrs42041
openSNPrs42041
23andMers42041
23andMe allrs42041
SNP Nexus

SNPshotrs42041
SNPdbers42041
MSV3drs42041
GWAS Ctlgrs42041
GMAF0.169
Max Magnitude
? (C;C) (C;G) (G;G) 28
GWAS
SNP rs42041
PubMedID [PMID 18794853OA-icon.png]
Condition Rheumatoid arthritis
Gene CDK6
Risk Allele G
pValue 4.00E-006
OR 1.11
95% CI


[PMID 19644859OA-icon.png] Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis


[PMID 20049410] A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis

[PMID 19435719OA-icon.png] Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.

[PMID 19674979OA-icon.png] Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.


GET Evidence
rs42041
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.148438
summary



[PMID 22328738OA-icon.png] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.


[PMID 25138370OA-icon.png] Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis