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rs42490

From SNPedia

Orientationplus
Stabilizedplus
Make rs42490(A;A)
Make rs42490(A;G)
Make rs42490(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position89766285
GeneRIPK2
is asnp
is mentioned by
dbSNPrs42490
ebirs42490
HLIrs42490
Exacrs42490
Varsomers42490
Maprs42490
PheGenIrs42490
hapmaprs42490
1000 genomesrs42490
hgdprs42490
ensemblrs42490
gopubmedrs42490
geneviewrs42490
scholarrs42490
googlers42490
pharmgkbrs42490
gwascentralrs42490
openSNPrs42490
23andMers42490
23andMe allrs42490
SNP Nexus

SNPshotrs42490
SNPdbers42490
MSV3drs42490
GWAS Ctlgrs42490
GMAF0.4343
Max Magnitude
? (A;A) (A;G) (G;G) 28
Variant in the RIPK2 gene associated with a reduced risk of leprosy in Asians, according to the 23andMe blog. The protective allele is A, and the odds ratio is 0.76.
GWAS snp
PMID [PMID 20018961]
Trait Leprosy
Title Genomewide Association Study of Leprosy
Risk Allele G
P-val 1E-16
Odds Ratio 1.32 [1.23-1.41]


[PMID 22504414] Association between C13ORF31, NOD2, RIPK2 and TLR10 polymorphisms and urothelial bladder cancer.


GET Evidence
rs42490
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.547619
summary



Leprosy Susceptibility