| Possibly slight 1.09x risk for development of MGUS |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
1
|
Normal risk for development of MGUS
|
| (A;G)
|
1
|
Possibly slight 1.09x risk for development of MGUS
|
| (G;G)
|
2
|
3.57x increased risk of MGUS
|
Very slightly increased risk for the development of MGUS (Monoclonal Gammopathy of Uncertain Significance). 95% CI .78-1.51. Plausible as the homozygote is more statistically significant and higher risk in the same study. Thus, the major, protective A allele can probably be thought of as acting in a dominant fashion in reducing risk of the development of MGUS. This genotype may be benign - any additional risk conferred is likely minimal.
