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rs4295627

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 1.61 1.85x higher risk for glioma development
(G;T) 1.3 1.36x higher risk for glioma development
(T;T) 0
ReferenceGRCh38 38.1/141
Chromosome8
Position129673211
is asnp
is mentioned by
dbSNPrs4295627
ebirs4295627
HLIrs4295627
Exacrs4295627
Varsomers4295627
Maprs4295627
PheGenIrs4295627
hapmaprs4295627
1000 genomesrs4295627
hgdprs4295627
ensemblrs4295627
gopubmedrs4295627
geneviewrs4295627
scholarrs4295627
googlers4295627
pharmgkbrs4295627
gwascentralrs4295627
openSNPrs4295627
23andMers4295627
23andMe allrs4295627
SNP Nexus

SNPshotrs4295627
SNPdbers4295627
MSV3drs4295627
GWAS Ctlgrs4295627
GMAF0.202
Max Magnitude1.61
? (G;G) (G;T) (T;T) 28

23andMe blog rs4295627 G 1.36 Glioma

GWAS snp
PMID [PMID 19578367OA-icon.png]
Trait Glioma
Title Genome-wide association study identifies five susceptibility loci for glioma
Risk Allele G
P-val 2E-18
Odds Ratio 1.36 [1.29-1.43]


[PMID 20462933] Interaction between 5 genetic variants and allergy in glioma risk

[PMID 20847058OA-icon.png] Genetic risk profiles identify different molecular etiologies for glioma

[PMID 20211558OA-icon.png] Genetic advances in glioma: susceptibility genes and networks

GWAS snp
PMID [PMID 21531791OA-icon.png]
Trait
Title Chromosome 7p11.2 (EGFR) variation influences glioma risk.
Risk Allele
P-val 5E-21
Odds Ratio 1.4000 [NR]

[PMID 20212223] New insights into susceptibility to glioma.

[PMID 21356187OA-icon.png] Distinct germ line polymorphisms underlie glioma morphologic heterogeneity.

[PMID 21825990] Genetic causes of glioma: new leads in the labyrinth.


GET Evidence
rs4295627
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.179688
summary



[PMID 23161787OA-icon.png] Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies


[PMID 26243184] An Updated and Comprehensive Meta-Analysis of Association Between Seven Hot Loci Polymorphisms from Eight GWAS and Glioma Risk


[PMID 26505354] CCDC26 rs4295627 polymorphism (8q24.21) and glioma risk: a meta-analysis