|?|| (A;A) (A;G) (G;G) ||28|
This SNP in the ACE
gene, also known as G12269A, is reported to influence how quickly African Americans respond to the anti-hypertensive drug ramipril
homozygotes are able to reach lower blood pressure levels upon treatment with ramipril
sooner than rs4344(A;G)
heterozygotes. The odds ratio reported for this study, comparing both homozygotes to heterozygotes, is 1.86 (CI: 1.32-3.23). [PMID 17885551
Note that this SNP is in almost complete linkage disequilibrium with the insertion/deletion ACE gene SNP.
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