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rs439401

From SNPedia

Orientationplus
Stabilizedplus
Make rs439401(C;C)
Make rs439401(C;T)
Make rs439401(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position44911194
GeneAPOE
is asnp
is mentioned by
dbSNPrs439401
ebirs439401
HLIrs439401
Exacrs439401
Varsomers439401
Maprs439401
PheGenIrs439401
hapmaprs439401
1000 genomesrs439401
hgdprs439401
ensemblrs439401
gopubmedrs439401
geneviewrs439401
scholarrs439401
googlers439401
pharmgkbrs439401
gwascentralrs439401
openSNPrs439401
23andMers439401
23andMe allrs439401
SNP Nexus

SNPshotrs439401
SNPdbers439401
MSV3drs439401
GWAS Ctlgrs439401
GMAF0.3944
Max Magnitude
? (C;C) (C;T) (T;T) 28

This appears to be the snp on the Illumina Human 550 which is closest to rs4420638

GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Triglycerides
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 2E-9
Odds Ratio 0.09 [NR] SD increase


GWAS snp
PMID [PMID 21123754OA-icon.png]
Trait
Title Genome-wide association study of CSF biomarkers A{beta}1-42, t-tau, and p-tau181p in the ADNI cohort.
Risk Allele
P-val 0.000001
Odds Ratio None None
GWAS snp
PMID [PMID 21386085OA-icon.png]
Trait
Title A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium
Risk Allele C
P-val 1E-8
Odds Ratio 0.2400 [0.16-0.32] unit increase


[PMID 21149302OA-icon.png] Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population

GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele T
P-val 1E-30
Odds Ratio 5.5000 None


[PMID 22419519] Impact of the Reelin signaling cascade (Ligands-Receptors-Adaptor Complex) on cognition in schizophrenia.


[PMID 18254975OA-icon.png] Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.


[PMID 18682748OA-icon.png] Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction.


[PMID 18823527OA-icon.png] A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.


[PMID 19118814OA-icon.png] Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.


[PMID 19299407OA-icon.png] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.


[PMID 19327864OA-icon.png] SNPit: a federated data integration system for the purpose of functional SNP annotation.


[PMID 19541455] Apolipoprotein-E gene variants associated with cardiovascular risk factors in antipsychotic recipients.


[PMID 19668339OA-icon.png] Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.


[PMID 19936222OA-icon.png] Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.


[PMID 20070850OA-icon.png] Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.


[PMID 20467002OA-icon.png] Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls.


[PMID 21283811OA-icon.png] Associations between APOE variants and metabolic traits and the impact of psychological stress.


GET Evidence
rs439401
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.650794
summary



[PMID 23435269OA-icon.png] Chronic Family Stress Moderates the Association between a TOMM40 Variant and Triglyceride Levels in Two Independent Caucasian Samples


[PMID 24160669OA-icon.png] Impact of APOE gene polymorphisms on the lipid profile in an Algerian population


[PMID 22430674OA-icon.png] Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.


[PMID 25098835OA-icon.png] Longitudinal analysis is more powerful than cross-sectional analysis in detecting genetic association with neuroimaging phenotypes