|?|| (C;C) (C;T) (T;T) ||28|
confer risk for estrogen receptor breast cancer
(ER)-positive tumors (OR = 1.27, P = 2.5E-12 for rs10941679) based on a study of 6,145 cases. [PMID 18438407
] From a DeCode user report, the risk allele appears to be T; this T;T individual reportedly has a 1.19x increased risk of breast cancer
] Novel Breast Cancer Risk Alleles and Interaction with Ionizing Radiation among U.S. Radiologic Technologists
[PMID 20140701] Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study
|| [PMID 21263130]
|| Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study
| Risk Allele
| Odds Ratio
|| 1.1700 [1.11-1.22]
[PMID 21791674] Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium
[PMID 22832384] Genetic variants at 5p12 and risk of breast cancer in Han Chinese
the two risk SNPs reported in the European population were neither associated with breast cancer risk in our Chinese population
[PMID 19330030] A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).
[PMID 20085711] Leveraging genetic variability across populations for the identification of causal variants.
|| Insufficiently evaluated pharmacogenetic
[PMID 22965832] Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.
[PMID 25002657] Breast cancer susceptibility variants and mammographic density phenotypes in Norwegian postmenopausal women