Have questions? Visit https://www.reddit.com/r/SNPedia

rs445925

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0
Make rs445925(C;T)
Make rs445925(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position44912383
GeneAPOC1
is asnp
is mentioned by
dbSNPrs445925
ebirs445925
HLIrs445925
Exacrs445925
Varsomers445925
Maprs445925
PheGenIrs445925
hapmaprs445925
1000 genomesrs445925
hgdprs445925
ensemblrs445925
gopubmedrs445925
geneviewrs445925
scholarrs445925
googlers445925
pharmgkbrs445925
gwascentralrs445925
openSNPrs445925
23andMers445925
23andMe allrs445925
SNP Nexus

SNPshotrs445925
SNPdbers445925
MSV3drs445925
GWAS Ctlgrs445925
GMAF0.1313
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20838585OA-icon.png]
Trait
Title Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa Heart Study
Risk Allele G
P-val 9E-19
Odds Ratio 11.96 [9.33-14.59] % SD increase


[PMID 21977987OA-icon.png] Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses

GWAS snp
PMID [PMID 21909108OA-icon.png]
Trait
Title Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
Risk Allele G
P-val 0.000004
Odds Ratio 1.2200 [1.12-1.32]

[PMID 22368281OA-icon.png] Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).

GWAS snp
PMID [PMID 23031429OA-icon.png]
Trait Apolipoprotein Levels
Title A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol.
Risk Allele G
P-val 2E-14
Odds Ratio .15 [0.11-0.19] unit increase
GWAS snp
PMID [PMID 23118302]
Trait Lipoprotein-associated phospholipase A2 activity and mass
Title Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
Risk Allele T
P-val 1E-56
Odds Ratio .07 [0.049-0.093] ng/ml decrease
GWAS snp
PMID [PMID 22916037OA-icon.png]
Trait Metabolite levels
Title Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
Risk Allele
P-val 6E-42
Odds Ratio NR NR


[PMID 23092954OA-icon.png] SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.

GWAS snp
PMID [PMID 24816252OA-icon.png]
Trait Blood metabolite ratios
Title An atlas of genetic influences on human blood metabolites.
Risk Allele A
P-val 5E-23
Odds Ratio .09 [0.071-0.107] unit increase


[PMID 26520901] Impact of carotid atherosclerosis loci on cardiovascular events