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rs4487645

From SNPedia

Orientationplus
Stabilizedplus
Make rs4487645(A;A)
Make rs4487645(A;C)
Make rs4487645(C;C)
ReferenceGRCh38 38.1/141
Chromosome7
Position21898622
GeneDNAH11
is asnp
is mentioned by
dbSNPrs4487645
ebirs4487645
HLIrs4487645
Exacrs4487645
Varsomers4487645
Maprs4487645
PheGenIrs4487645
hapmaprs4487645
1000 genomesrs4487645
hgdprs4487645
ensemblrs4487645
gopubmedrs4487645
geneviewrs4487645
scholarrs4487645
googlers4487645
pharmgkbrs4487645
gwascentralrs4487645
openSNPrs4487645
23andMers4487645
23andMe allrs4487645
SNP Nexus

SNPshotrs4487645
SNPdbers4487645
MSV3drs4487645
GWAS Ctlgrs4487645
GMAF0.2268
Max Magnitude
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 22120009]
Trait
Title Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.
Risk Allele C
P-val 3E-14
Odds Ratio 1.3800 None
GWAS snp
PMID [PMID 23502783]
Trait Multiple myeloma (hyperdiploidy)
Title The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Risk Allele C
P-val 1E-9
Odds Ratio 1.43 [1.27-1.60]


[PMID 24449210] Inherited genetic susceptibility to monoclonal gammopathy of unknown significance


[PMID 25480495OA-icon.png] The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells