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rs449647

From SNPedia

Orientationminus
Stabilizedplus
Geno Mag Summary
(A;A) 2 lower levels of ApoE
(A;T) 1.2 Possibly lower levels of ApoE
(T;T) 1.5 Normal levels of ApoE
ReferenceGRCh38 38.1/142
Chromosome19
Position44905307
GeneAPOE
is asnp
is mentioned by
dbSNPrs449647
ebirs449647
HLIrs449647
Exacrs449647
Varsomers449647
Maprs449647
PheGenIrs449647
hapmaprs449647
1000 genomesrs449647
hgdprs449647
ensemblrs449647
gopubmedrs449647
geneviewrs449647
scholarrs449647
googlers449647
pharmgkbrs449647
gwascentralrs449647
openSNPrs449647
23andMers449647
23andMe allrs449647
SNP Nexus

SNPshotrs449647
SNPdbers449647
MSV3drs449647
GWAS Ctlgrs449647
GMAF0.1758
Max Magnitude2
[PMID 19172988OA-icon.png] Significant Alzheimer's disease associations with were found for rs449647(A;A) and rs405509(G;G) genotypes (positive), and rs449647(A;T) and rs405509(T;T)


[PMID 21263195] An APOE Haplotype Associated with Decreased ?4 Expression Increases the Risk of Late Onset Alzheimer's Disease


[PMID 22028770OA-icon.png] APOE Genotype-Function Relationship: Evidence of -491 A/T Promoter Polymorphism Modifying Transcription Control but Not Type 2 Diabetes Risk

[PMID 17434289OA-icon.png] Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association.


[PMID 18161859OA-icon.png] Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13?


[PMID 25085564OA-icon.png] Influence of multiple