|?|| (C;C) (C;T) (T;T) ||28|
also referred to as 1766A/G
plos rs450046 was most strongly positively associated with schizophrenia in families.
[PMID 19232576] rs372055(C), rs450046(G), rs385440(A) haplotype carriers (n = 32) exhibited attenuated PPI + verbal memory (p < .001) as well as higher anxiety (p < .004) and schizotypy (p < .008) compared to noncarriers (n = 185)
[PMID 17708757] Genome bioinformatic analysis of nonsynonymous SNPs.
[PMID 18408230] Structural cerebral variations as useful endophenotypes in schizophrenia: do they help construct "extended endophenotypes"?
[PMID 18989458] Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function.
[PMID 19693005] Executive function, neural circuitry, and genetic mechanisms in schizophrenia.
|| not reviewed
|| Insufficiently evaluated not reviewed