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rs4505848

From SNPedia

Orientationplus
Stabilizedplus
Make rs4505848(A;A)
Make rs4505848(A;G)
Make rs4505848(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position122211337
GeneKIAA1109
is asnp
is mentioned by
dbSNPrs4505848
ebirs4505848
HLIrs4505848
Exacrs4505848
Varsomers4505848
Maprs4505848
PheGenIrs4505848
hapmaprs4505848
1000 genomesrs4505848
hgdprs4505848
ensemblrs4505848
gopubmedrs4505848
geneviewrs4505848
scholarrs4505848
googlers4505848
pharmgkbrs4505848
gwascentralrs4505848
openSNPrs4505848
23andMers4505848
23andMe allrs4505848
SNP Nexus

SNPshotrs4505848
SNPdbers4505848
MSV3drs4505848
GWAS Ctlgrs4505848
GMAF0.3356
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 19302705OA-icon.png] Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.
GWAS snp
PMID [PMID 19430480OA-icon.png]
Trait Type 1 diabetes
Title Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
Risk Allele
P-val 5E-13
Odds Ratio NR NR
OMIM611598
DescCELIAC DISEASE, SUSCEPTIBILITY TO, 6; CELIAC6
Variant
Relatedalso
[PMID 22065918OA-icon.png] CFH 184G as a genetic risk marker for anterior uveitis in Chinese females

[PMID 17558408OA-icon.png] A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.

[PMID 17999365OA-icon.png] Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.

[PMID 20553587OA-icon.png] Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.


GET Evidence
rs4505848
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.296875
summary



[PMID 25661663] Association of 32 type 1 diabetes risk loci in Pakistani patients